IV Symposium
Glia Diversity in Neuromodulation
and Neurodegeneration May 29, 2019 - FFULisboa
|
95 participants
8 invited experts 5 selected oral presentations 15 selected poster pitch presentations 16 poster presentations |
The Portuguese Glial Network invites you to attend and participate at the IV Symposium of the Portuguese Glial Network on May 29th, 2019. The Symposium will be held at the Faculty of Pharmacy of the University of Lisbon (FFULisboa).
This Glial meeting will focus on indirect and direct conversion of somatic cells into neural cells to model diseases of the central nervous system (CNS), and on new evidences about the specific roles of different glial cell types, their regional diversity, and contribution to disease onset, progression and neurodegeneration. Emphasis will be given in how glial cells and neurons are intermingled and mutually depend on each other to maintan CNS homeostasis. The Symposium will provide forward looking activities where students will have the opportunity to interact, share and discuss their research data, as well as receive constructive feedback from scientists and leaders in the field. |
Laurent Roybon
Lund University, Sweden "Can induced pluripotent stem cells help us decipher the role of glial cells in Parkinson’s disease?" |
Kathrin Meyer
Ohio State University, USA "Astrocyte in vitro models for neurological and neurodegenerative disorders" |
Tarja Malm
University of Eastern Finland, Finland "Modeling microglial dysfunctions in AD" |
Tanja Kuhlmann
University Hospital Münster, Germany "How to wrap the myelin: New approaches to understand myelin diseases" |
Scientific Program
09:30-10:00 REGISTRATION
10:00 WELCOME
Dora Brites (iMed.ULIsboa, University of Lisbon, Portugal)
10:15 PLENARY LECTURE | ROCHE - "Can induced pluripotent stem cells help us decipher the role of glial cells in Parkinson’s disease?"
Laurent Roybon (Lund University, Sweden)
11:00 COFFEE BREAK
11:30-13:00 | SESSION I – ASTROCYTES: BIOLOGY AND PATHOLOGY
Chair: João Oliveira (ICVS, University of Minho, Portugal)
11:30 “Skin derived astrocytes as a tool to study disease severity and drug responsiveness”
Invited Speaker: Kathrin Meyer (The Ohio State University, US)
12:00 “Unravelling NLRP3 inflammasome expression in astrocytes”
Claudia Valente (IMM, University of Lisbon, PT)
12:20 “Astrocyte phenotypic aberrancy differs from the spinal cord to the cortical brain in ALS disease”
Ana Rita Vaz (iMed.ULisboa, University of Lisbon, PT)
12:40 “The role of astrocytic calcium signaling in the cognitive function”
Sónia Guerra-Gomes (ICVS School of Medicine, University of Minho, PT)
12:50 “Microglial and astrocytic pathology in a mouse model of Machado-Joseph disease”
Ana Bela Campos (ICVS School of Medicine, University of Minho, PT)
13:00-14:00 – LUNCH
14:00:15:30 | SESSION II – MICROGLIA ACTIVATION AND IMMUNOREGULATION
Chair: Francisco Ambrósio (CNC.IBILI Consortium, University of Coimbra, Portugal)
14:00 “Modeling microglial dysfunctions in AD”
Invited Speaker: Tarja Malm (University of Eastern Finland, FI)
14:30 “Controlling microglia-mediated neuroinflammation in retinal diseases: role of adenosine A2A receptors”
Raquel Santiago (CIBB, University of Coimbra, PT)
14:50 "Emerging roles of glial Striatal-Enriched Protein Tyrosine Phosphatase (STEP)"
Graça Baltazar (CICS, University of Beira Interior, PT)
15:10 “TNF and glutamate dependent microglia reactivity under a psychoactive drug”
Teresa Summavielle (i3S/IBMC, University of Porto, PT)
15:20 “IL-4 skews the microglial developmental program during cerebellar maturation”
Joana Guedes (CIBB, University of Coimbra, PT)
15:30:17:00 | SESSION III - NETWORK WITH SCIENTISTS AND INTERACTIVE POSTER SESSION
This session, besides allowing poster viewing, features discussion groups that are led by moderators who ensure focused conversations around the key issues listed in each selected poster by session topic. Attendees should bring their printed A4 poster copies and informal setting will facilitate sharing of ideas and active networking.
(With coffee and drinks, Library of the Faculty of Pharmacy)
10:00 WELCOME
Dora Brites (iMed.ULIsboa, University of Lisbon, Portugal)
10:15 PLENARY LECTURE | ROCHE - "Can induced pluripotent stem cells help us decipher the role of glial cells in Parkinson’s disease?"
Laurent Roybon (Lund University, Sweden)
11:00 COFFEE BREAK
11:30-13:00 | SESSION I – ASTROCYTES: BIOLOGY AND PATHOLOGY
Chair: João Oliveira (ICVS, University of Minho, Portugal)
11:30 “Skin derived astrocytes as a tool to study disease severity and drug responsiveness”
Invited Speaker: Kathrin Meyer (The Ohio State University, US)
12:00 “Unravelling NLRP3 inflammasome expression in astrocytes”
Claudia Valente (IMM, University of Lisbon, PT)
12:20 “Astrocyte phenotypic aberrancy differs from the spinal cord to the cortical brain in ALS disease”
Ana Rita Vaz (iMed.ULisboa, University of Lisbon, PT)
12:40 “The role of astrocytic calcium signaling in the cognitive function”
Sónia Guerra-Gomes (ICVS School of Medicine, University of Minho, PT)
12:50 “Microglial and astrocytic pathology in a mouse model of Machado-Joseph disease”
Ana Bela Campos (ICVS School of Medicine, University of Minho, PT)
13:00-14:00 – LUNCH
14:00:15:30 | SESSION II – MICROGLIA ACTIVATION AND IMMUNOREGULATION
Chair: Francisco Ambrósio (CNC.IBILI Consortium, University of Coimbra, Portugal)
14:00 “Modeling microglial dysfunctions in AD”
Invited Speaker: Tarja Malm (University of Eastern Finland, FI)
14:30 “Controlling microglia-mediated neuroinflammation in retinal diseases: role of adenosine A2A receptors”
Raquel Santiago (CIBB, University of Coimbra, PT)
14:50 "Emerging roles of glial Striatal-Enriched Protein Tyrosine Phosphatase (STEP)"
Graça Baltazar (CICS, University of Beira Interior, PT)
15:10 “TNF and glutamate dependent microglia reactivity under a psychoactive drug”
Teresa Summavielle (i3S/IBMC, University of Porto, PT)
15:20 “IL-4 skews the microglial developmental program during cerebellar maturation”
Joana Guedes (CIBB, University of Coimbra, PT)
15:30:17:00 | SESSION III - NETWORK WITH SCIENTISTS AND INTERACTIVE POSTER SESSION
This session, besides allowing poster viewing, features discussion groups that are led by moderators who ensure focused conversations around the key issues listed in each selected poster by session topic. Attendees should bring their printed A4 poster copies and informal setting will facilitate sharing of ideas and active networking.
(With coffee and drinks, Library of the Faculty of Pharmacy)
Poster viewing
15:30 – 16:00 Presenting authors are kindly requested to be near their posters for informal discussion |
Table 1 – Astrocytes
Discussion Leaders: João Oliveira and Graça Baltazar 16:00 Ana Bernardo, CIBB, UCoimbra 16:15 Cátia Gomes, iMed.ULisboa 16:30 Joana Gomes, IMM, ULisboa |
Table 2 – Microglia
Discussion Leaders: Francisco Ambrósio and Tarja Malm 16:00 Gonçalo Garcia, iMed.ULisboa 16:15 Illyane Lima, CEDOC-NMS 16:30 Camila Cabral, IBMC/i3S, UPorto |
Table 3 – Oligodendrocytes
Discussion Leaders: Ana Seixas and Tanja Kuhlmann 16:00 Joana Mateus, iMM, ULisboa 16:15 Catarina Barros, iMed.ULisboa 16:30 Rita Soares, IMM, ULisboa |
Table 4 – Glial-neuronal interactions
Discussion Leaders: Laurent Roybon and Ana Rita Vaz 16:00 Haissa de Castro, U. Lausanne 16:15 Pedro Dionísio, iMed.ULisboa 16:30 Catarina Sequeira, iMed.ULisboa |
Table 5 – Mixed topics
Discussion Leaders: Adelaide Fernandes and João Relvas 16:00 Diana Nascimento, ICVS, UMinho 16:15 Andreia Pinho, ICVS, UMinho 16:30 Inês Aires, CIBB, UCoimbra |
17:00-18:00 | SESSION IV – OLIGODENDROCYTES: MYELIN DYSFUNCTION AND RENEWAL
Chair: João Relvas (i3S/IBMC, University of Porto, Portugal)
17:00 “Actin dynamics and mechanisms of regulation in oligodendrocyte biology”
Ana Seixas (i3S/IBMC, University of Porto, PT)
17:20 “The paradigm shift on remyelination failure problem – do mechanical properties play a crucial role?”
Eva Carvalho (i3S/IBMC, University of Porto, PT)
17:30 “How to wrap the myelin: New approaches to understand myelin diseases”
Invited Speaker: Tanja Kuhlmann (Neuropathology, University of Munster, DE)
18:00 | CLOSING
Abstract book

abstract_book.pdf |
Registration
|
Venue |
Registration and abstract submission for the IV Symposium is closed.
Important dates
Registration deadline: May 10
Abstract submission: April 26 |
Faculty of Pharmacy, University of Lisbon
Auditorium Maria Odette Santos-Ferreira Av. Prof Gama Pinto, Lisboa |